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Amanda McCann Selected Research

Messenger RNA (mRNA)

12/20215-AZA-dC induces epigenetic changes associated with modified glycosylation of secreted glycoproteins and increased EMT and migration in chemo-sensitive cancer cells.
1/2014The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.
6/2008Small interfering RNAs induce macrophage migration inhibitory factor production and proliferation in breast cancer cells via a double-stranded RNA-dependent protein kinase-dependent mechanism.
11/2007Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.

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Amanda McCann Research Topics

Disease

20Neoplasms (Cancer)
12/2021 - 11/2007
11Breast Neoplasms (Breast Cancer)
04/2021 - 06/2002
7Ovarian Neoplasms (Ovarian Cancer)
12/2021 - 07/2010
4Triple Negative Breast Neoplasms
12/2021 - 06/2015
4Neoplasm Metastasis (Metastasis)
04/2021 - 11/2011
4Hypoxia (Hypoxemia)
04/2014 - 10/2009
3Carcinoma (Carcinomatosis)
03/2009 - 06/2002
2Multiple Myeloma
01/2020 - 01/2019
2Carcinogenesis
01/2019 - 06/2008
2Chromosomal Instability (Chromosome Stability)
05/2015 - 07/2010
1Colorectal Neoplasms (Colorectal Cancer)
01/2021
1Disease Progression
12/2020
1Melanoma (Melanoma, Malignant)
12/2020
1Inflammation (Inflammations)
01/2020
1Hematologic Neoplasms (Hematological Malignancy)
01/2019
1Aneuploidy (Aneuploid)
01/2019
1Genomic Instability
01/2018
1Retinoblastoma (Glioblastoma, Retinal)
05/2015
1Glaucoma
12/2014
1Embryonal Carcinoma
01/2014
1Protein Deficiency
04/2012
1Ovarian Epithelial Carcinoma
11/2011
1Adenocarcinoma
06/2008

Drug/Important Bio-Agent (IBA)

7Proteins (Proteins, Gene)FDA Link
01/2021 - 11/2007
5DNA (Deoxyribonucleic Acid)IBA
12/2021 - 09/2008
4Messenger RNA (mRNA)IBA
12/2021 - 11/2007
4Polysaccharides (Glycans)IBA
12/2021 - 11/2011
4Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2020
4Paclitaxel (Taxol)FDA LinkGeneric
01/2020 - 04/2012
3Glycoproteins (Glycoprotein)IBA
12/2021 - 11/2011
3MethyltransferasesIBA
12/2021 - 04/2014
3EnzymesIBA
12/2020 - 04/2014
3Progesterone Receptors (Progesterone Receptor)IBA
12/2020 - 12/2007
3Interleukin-6 (Interleukin 6)IBA
01/2020 - 10/2009
3Small Interfering RNA (siRNA)IBA
01/2020 - 11/2007
2human ERBB2 proteinIBA
12/2020 - 03/2018
2Estrogen ReceptorsIBA
03/2018 - 08/2005
2MicroRNAs (MicroRNA)IBA
05/2015 - 01/2014
2ParaffinIBA
01/2014 - 11/2007
2CytokinesIBA
10/2009 - 06/2008
2Insulin-Like Growth Factor II (Somatomedin A)IBA
03/2009 - 11/2008
2Protein Isoforms (Isoforms)IBA
12/2007 - 06/2002
2Estrogen Receptor alphaIBA
12/2007 - 11/2007
1von Willebrand FactorIBA
04/2021
1Phosphatidylinositols (Phosphatidylinositol)IBA
01/2021
1LectinsIBA
01/2021
1Histone Deacetylase 6IBA
12/2020
1Histones (Histone)IBA
12/2020
1histone deacetylase 3IBA
01/2020
1Histone Deacetylases (Histone Deacetylase)IBA
01/2020
1ErbB Receptors (EGF Receptor)IBA
03/2018
1GalactosidasesIBA
05/2015
1Enhancer of Zeste Homolog 2 ProteinIBA
04/2015
1LipofuscinIBA
12/2014
1myasthenia gravis anti-skeletal muscle antibody (ASMA)IBA
04/2014
1CollagenIBA
04/2014
1DecitabineFDA Link
11/2011
1ChromatinIBA
07/2010
1Transcription Factors (Transcription Factor)IBA
05/2010
1Interleukin-1beta (Interleukin 1 beta)IBA
10/2009
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2009
1Interleukin-8 (Interleukin 8)IBA
10/2009
1Insulin-Like PeptidesIBA
03/2009
1Cadherins (E-Cadherin)IBA
11/2008
1progesterone receptor BIBA
09/2008
1RNA (Ribonucleic Acid)IBA
09/2008
1SodiumIBA
09/2008
1Protein Kinases (Protein Kinase)IBA
06/2008
1Double-Stranded RNA (RNA, Double Stranded)IBA
06/2008
1Macrophage Migration-Inhibitory FactorsIBA
06/2008
1Biological ProductsIBA
06/2008
1Taxoids (Taxanes)IBA
04/2008
1Estrogens (Estrogen)FDA Link
12/2007
1Hormones (Hormone)IBA
12/2007
1ProgesteroneFDA LinkGeneric
12/2007
1Fulvestrant (Faslodex)FDA Link
11/2007
1Estrogen Receptor Modulators (Antiestrogen)IBA
11/2007

Therapy/Procedure

10Therapeutics
12/2021 - 08/2005
4Drug Therapy (Chemotherapy)
01/2021 - 05/2015
1Cystectomy
11/2008